prof. dr hab. Moraczewska JoannaPublikacje

prof. dr hab. Moraczewska JoannaPublikacje

Oryginalne prace doświadczalne:

 

  1. Jerzmanowski, A., Moraczewska, J. (1987) A charged contaminant prevents Physarum chromatin from aggregating. Biochim.Biophys.Acta 910, 111-115.
  2. Jerzmanowski, A., Moraczewska, J. (1988) Distribution of postsynthetic methylation sites in Physarum histone H1. Mol.Biol.Rep.13, 97-101.
  3. Strzelecka-Gołaszewska, H., Boguta, G., Zmorzyński, S., Moraczewska, J. (1989) Biochemical and theoretical approach to localization of metal-ion-binding sites in the actin primary sites in the actin primary structure. Eur.J.Biochem. 182, 299-305.
  4. Strzelecka-Gołaszewska, H., Moraczewska, J., Khaitlina, S.Y., Mossakowska, M. (1993) Localization of the tightly bound divalent-cation-dependent and nucleotide-dependent conformational changes in G-actin using limited proteolytic digestion. Eur.J.Biochem. 211, 731-748.
  5. Khaitlina, S.Y., Moraczewska, J., Strzelecka-Gołaszewska, H. (1993) The actin-actin interactions involving the N-terminus portion of the DNaseI-binding-loop are crucial for stabilization of the actin filament. Eur.J.Bioch. 218, 911-920.
  6. Mossakowska, M., Moraczewska, J., Khaitlina, S.Y., Strzelecka-Gołaszewska, H. (1993) Proteolytic removal of three C-terminal residues of actin alters the monomer-monomer interactions. Biochem.J. 289, 897-902.
  7. Strzelecka-Gołaszewska, H., Mossakowska, M., Woźniak, A., Moraczewska, J., Nakayama, H. (1995) Long-range conformational effects of proteolytic removal of the last three residues of actin. Biochem.J. 307, 527-534.
  8. Moraczewska, J., Strzelecka-Gołaszewska, H., Moens, P.,D.,J., dos Remedios, C.G. (1996) Structural changes in subdomain 2 of G-actin observed by fluorescence spectroscopy. Biochem.J. 317, 605-611.
  9. Moraczewska, J., Wawro, B., Seguro, K., Strzelecka-Gołaszewska, H. (1999) Divalent  Cation-, and Polymerization-Dependent Changes in the Conformation of Subdomain 2 of Actin. Biophys.J. 77, 373-377.
  10. Moraczewska, J., Nicholson-Flynn, K., Hitchocock-DeGregori, S.E. (1999) The Ends of Tropomyosin Are Major Determinants of Actin Affinity and Myosin Subfragment 1-Induced Binding to F-Actin in the Open State. Biochemistry 38, 15885-15892.
  11. Moraczewska, J., Hitchcock-DeGregori, S.E. (2000) Independent Functions for the N- and C-termini in the Overlap Region of Tropomyosin. Biochemistry 39, 6891-6897.
  12. Borovikov Y.S., Moraczewska J., Khoroshev M.I., Strzelecka-Gołaszewska H. (2000) Proteolytic Cleavage of Actin Within the DNase-I-Binding Loop Changes the Conformation of F-actin and Its Sensitivity to Myosin Binding. Biochim. Biophys. Acta 1478, 138-151.
  13. Moraczewska, J., Greenfield, N.J., Liu, Y., Hitchcock-DeGregori, S.E. (2000) Alteration of Tropomyosin Function and Folding by a Nemaline Myopathy-Causing Mutation. Biophys. J. 79, 3217-3225.
  14. Hitchcock-DeGregori, S. E., Song, Y., Moraczewska, J. (2001) Importance of Internal Regions and the Overall Length of Tropomyosin for Actin Binding and Regulatory Function. Biochemistry 40, 2104-2112.
  15. Moraczewska, J., Gruszczyńska-Biegała, J., Rędowicz M.J., Khaitlina, S., Strzelecka-Gołaszewska, H. (2004) The Dnase-I Binding Loop May Play a Role in the Regulation of Actin-Myosin Interaction by Tropomyopsin/Troponin. J.Biol.Chem. 279, 31197-31204.
  16. Kłopocka ,W., Moraczewska, J., Rędowicz, M.J. (2005) Characterization of Rac/PAK pathway in Amoeba proteus. Protoplasma, 225, 77-84.
  17. Śliwińska M., Skórzewski R., Moraczewska J. (2008) Role of Actin C Terminus in Regulation of Striated Muscle Thin Filament. Biophys. J.94, 1341-1347.
  18. Skórzewski, R., Śliwińska, M., Borys, D., Sobieszek, A., Moraczewska J. (2009) Effect of actin C-terminal modification on tropomyosin isoforms binding and thin filament regulation. Biochim.Biophys. Acta – Prot. Proteom. 1794, 237-243.
  19. Skórzewski R, Robaszkiewicz K, Jarzębińska J, Suder P, Silberring J, Moraczewska J. (2009) Differential binding of tropomyosin isoforms to actin modified with m-maleimidobenzoyl-N-hydroxysuccinimide ester and fluorescein-5-isothiocyanate. Anal Biochem. 1; 394: 48-55.
  20. Śliwińska M., Żukowska M., Borys D., Moraczewska J. (2011) Different positions of tropomyosin on actin filament are determined by specific overlaps of end-to-end overlaps. Cytoskeleton 68, 300-312.
  21. Robaszkiewicz K., Dudek E., Kasprzak, A.A., Moraczewska J. (2012) Functional effects of congenital myopathy related mutations in gamma-tropomyosin gene. Biochim.Biophys.Acta - Mol. Basis Dis.1822, 1562-1569.
  22. Jurewicz E., Ostrowska Z., Jóźwiak J., Rędowicz M.J., Leśniak W., Moraczewska J., Filipek A. (2013) CacyBP/SIP as a novel modulator of the thin filament. Biochim. Biophys. Acta – Mol. Cell Res. 1833, 761-766.
  23. Jędrzejewska B, Bajorek A, Moraczewska J. (2013) Interaction of carbocyanine dyes with DNA: synthesis and spectroscopic studies. Appl. Spectrosc. 67 (6):672-80.
  24. Śliwińska M, Moraczewska J. (2013) Structural differences between C-terminal regions of tropomyosin isoforms. PeerJ. Oct 15;1:e181.
  25. Robaszkiewicz K., Ostrowska Z., Cyranka-Czaja A., Moraczewska J. (2015) Impaired tropomyosin-troponin interactions reduce activation of the actin thin filament Biochim.Biophys. Acta – Prot. Proteom.1854, 381-390.
  26. Robaszkiewicz K, Ostrowska Z, Marchlewicz K, Moraczewska J. (2016) Tropomyosin isoforms differentially modulate the regulation of actin filament polymerization and depolymerization by cofilins. FEBS J. 283(4):723-737.
  27. Borovikov YS, Rysev NA, Chernev AA, Avrova SV, Karpicheva OE, Borys D, Śliwińska M, Moraczewska J. (2016) Abnormal movement of tropomyosin and response of myosin heads and actin during the ATPase cycle caused by the Arg167His, Arg167Gly and Lys168Glu mutations in TPM1 gene. Arch Biochem Biophys. 606:157-166.
  28. Ostrowska Z, Robaszkiewicz K, Moraczewska J. (2017) Regulation of actin filament turnover by cofilin-1 and cytoplasmic tropomyosin isoforms. Biochim Biophys Acta – Prot. Proteom. 1865: 88-98 (doi: 10.1016/j.bbapap.2016.09.019).
  29. Borovikov YS, Rysev NA, Avrova SV, Karpicheva OE, Borys D, Moraczewska J. Molecular mechanisms of deregulation of the thin filament associated with the R167H and K168E substitutions in tropomyosin Tpm1.1. Arch Biochem Biophys. 2016 Dec 9. pii: S0003-9861(16)30557-4.(doi: 10.1016/j.abb.2016.12.004).

Artykuły przeglądowe:

 

  1. Moraczewska, J. (2001) Tropomiozyna – regulatorowe białko filamentu cienkiego. Kosmos, 50, 236-270.
  2. Moraczewska, J. (2002) Structural determinants of cooperativity in acto-myosin interactions. Acta Biochim.Pol. 49 (4), 805-812. (w j. angielskim)
  3. Moraczewska J. (2009) Rola izoform tropomiozyny w różnicowaniu funkcji filamentów aktynowych. Post. Bioch. 55: 201-206.
  4. Robaszkiewicz K., Moraczewska J. (2011) Wrodzone miopatie – choroby mięśni szkieletowych związane z zaburzeniami struktury i funkcji filamentu aktynowego. Post.Hig.Med.Dośw., 65, 347-356.
  5. Moraczewska J. Śliwińska M., Rędowicz M.J. (2012) Udział jonów wapnia w regulacji oddziaływań aktyny z miozyną. Post. Bioch. 58, .437-451.
  6. Rędowicz MJ, Moraczewska J. (2015) Insight into muscle physiology through understanding mechanisms of muscle pathology. J Muscle Res Cell Motil. 36(6):359-361. (w j. angielskim)
  7. Ostrowska Z., Moraczewska J. (2016) Kofilina – białko kontrolujące dynamikę filamentów aktynowych. Post.Hig.Med.Dośw., in press.

 

prof. dr hab. Moraczewska Joanna